Organo-Metalloid Compounds
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- (19)
- (139)
- (2)
- (10)
- (1)
- (1)
- (27)
- (20)
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- (62)
- (96)
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- (206)
- (153)
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- (1)
- (1)
- (1)
- (251)
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- (9)
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- (1)
- (1)
- (1)
- (1)
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- (1)
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- (9)
- (1)
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- (1)
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- (1)
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Filtered Search Results
Ambeed AMBEED
5000847847 BROMOACETAMIDO-PEG3-C2- 1G
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5000848247 BROMOACETAMIDO-PEG3-C2- 100MG
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eMolecules EMOLECULES INC
5000841378 FOLATE-PEG3-AZIDE 25MG
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5000866889 TETRAETHYL ETHENE-11-DIYLB 1GR
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Medchemexpress LLC BOCNH-PEG5-CH2CH2BR 50MG
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5000205718 BOCNH-PEG5-CH2CH2BR 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000744580 N-AZIDO-PEG3-N-BOC 250MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
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5000745668 AMINO-BIS-PEG3-BCN 1MG
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Ambeed AMBEED
5000869663 TETRAETHYL ETHENE-11-DIY 100MG
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5000895810 N-PEG3-ACID-N-BISPEG3-AM 100MG
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5000895811 N-PEG3-ACID-N-BISPEG3-AM 250MG
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5000891055 MAL-PEG3-NH2 TFA 250MG
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Accela Chembio Inc 2 | 2'-bis(trifluoromethyl)benzidine | 100g | 341-58-2 | MFCD00190155 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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2 | 2'-bis(trifluoromethyl)benzidine | 100g | 341-58-2 | MFCD00190155 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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Medchemexpress LLC AK-778-XXMU | 1227045-76-2 | 99.9% | C22H17ClN2O3 | 1 ML
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AK-778-XXMU is a potent DNA binding inhibitor 2 (ID2) antagonist with a KD of 129 nM. It can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and exhibits significant cancer-suppressing potency. The compound acts by inhibiting the ID2-KDR signaling axis, leading to the down-regulation of angiogenic factors (VEGFA) and invasion-related proteins (MMP2/9), and the up-regulation of the tumor suppressor factor (PTEN). It is suitable for the study of glioma.
- Potent ID2 antagonist with a KD of 129 nM
- Inhibits cell migration and invasion in glioma cell lines
- Induces apoptosis
- Exhibits significant cancer-suppressing potency
- Down-regulates angiogenic factors (VEGFA)
- Down-regulates invasion-related proteins (MMP2/9)
- Up-regulates tumor suppressor factor (PTEN)
- Inhibits tumor growth in U87 glioma xenograft mice model
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Medchemexpress LLC Ps-1145 | 431898-65-6 | MFCD08705411 | 99.9% | 322.75 | C17H11ClN4O | 10 MG
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PS-1145 is a small-molecule inhibitor of IκB kinase (IKK) used in research to block NF-κB signaling and induce apoptosis in cell models. It is supplied as a powder with documented solubility and storage recommendations for experimental use.
- Potent IKK inhibitor with IC50 of 88 nM.
- High chemical purity (99.88%).
- Provided as a powder for convenient handling and formulation.
- Soluble in DMSO at 20.83 mg/mL; multiple in vitro formulations available.
- Stable under recommended storage conditions for long-term use.
- Suitable for in vitro studies of NF-κB signaling and apoptosis pathways.
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Medchemexpress LLC AK-778-XXMU | 1227045-76-2 | 99.9% | C22H17ClN2O3 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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AK-778-XXMU is a potent DNA binding inhibitor 2 (ID2) antagonist with a KD of 129 nM, used for the study of glioma. It inhibits the ID2-KDR signaling axis, leading to the downregulation of downstream angiogenic factors and invasion-related proteins, and the upregulation of the tumor suppressor factor PTEN. This compound demonstrates significant cancer-suppressing potency by inhibiting cell migration and invasion of glioma cell lines and inducing apoptosis.
- Potent ID2 antagonist with a KD of 129 nM
- Inhibits cell migration and invasion of glioma cell lines
- Induces apoptosis
- Inhibits ID2-KDR signaling axis
- Downregulates angiogenic factors (VEGFA) and invasion-related proteins (MMP2/9)
- Upregulates tumor suppressor factor (PTEN)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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